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2.2 Mechanism of ferroptosis occurrence 2.2.1 Core regulatory pathways 2.2.1.1 System xc /GSH/GPX4 signaling as primary regulatory hub Ferroptosis regulation is widely recognized as primarily involving the constitutive inhibition of system Xc , which triggers a cascade leading to glutathione (GSH) exhaustion and GPX4 functional impairment
35050061, Gibco, Waltham, MA), and 10% FBS (Cat
Adenosine receptors in neurology and psychiatry
Immunofluorescence tissues were mounted with ProLong Gold (Life Technologies, Cat# P36934), while H&E and immunohistochemistry tissues were mounted with Permount mounting media (Fisher Scientific, Cat# SP15500) and coverslipped for imaging
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Ketone metabolism in the failing heart
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